For more information see the syllabus for Winter 2014 class














Functional Genomics and Systems Biology

2 credit hours, Course Reference Number 20374 (IBS7030) / 21722 (MBG7030)

Winter 2015

Mondays 6:00 - 8:00 PM room 2268 Scott Hall



The fundamental goal of Systems Biology research, and perhaps of most biomedical research, is to understand how biological systems work - how systems develop and respond to environmental signals, how their normal function can break down in diseases, and how they can be manipulated, for example, to alleviate the burden of disease. The genome sequences of humans and model organisms have provided researchers with powerful tools to study biological systems.  They have also revealed thousands of genes whose functions we do not fully understand.  The field of Functional Genomics emerged to help solve this problem.  Functional genomic studies use high throughput or high content technologies and analysis methods to collect and integrate functional information on large sets of genes.


This course provides an introduction to the theory and latest advances in Functional Genomics technologies and Systems Biology research. A major focus is placed on understanding how the data from these technologies can be interpreted to derive testable hypotheses about the functions of genes and entire biological systems. Topics include Genomics, Transcriptomics, Proteomics, Interactomics, Phenomics, Network Biology, Systems Biology, and Synthetic Biology. The course relies heavily on recent literature relevant to the theory and application of Functional Genomics technologies and Systems Biology.



Open to Wayne State University Graduate Students who have taken IBS7010 Molecular Biology and IBS7020 Cell Biology or by permission from the course director (



This course is cross-listed as part of the Interdisciplinary Biomedical Sciences (IBS) curriculum (IBS7030) and the Molecular Biology and Genetics (MBG) curriculum (MBG7030).  Consult with your Graduate Advisor or the course director about how credit for this course may be used to fulfill the requirements of your program.


Course Director:

For more information contact Dr. Russ Finley (phone 577-7845; E-mail


Web site: